The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2012

Filed:

Dec. 13, 2006
Applicants:

Brooks J. Story, Franklin, MA (US);

Ed Yiling LU, Chestnut Hill, MA (US);

Donna Torres, Atileboro, MA (US);

Inventors:

Brooks J. Story, Franklin, MA (US);

Ed Yiling Lu, Chestnut Hill, MA (US);

Donna Torres, Atileboro, MA (US);

Assignee:

DePuy Mitek, Inc., Raynham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method of using locally administered collagenase as a non-invasive means of enhancing cell release from the cartilage or fibrocartilage tissues adjacent to a disease or injury site. The subsequent migration of cells from these tissues into the lesion or wound, followed by deposition of the appropriate extracellular matrix, results in closure of the lesion or fusion of a tissue gap.


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