The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2012

Filed:

Aug. 12, 2006
Applicants:

Christopher G. Rylander, Blacksburg, VA (US);

Thomas E. Milner, Austin, TX (US);

Oliver Stumpp, Palo Alto, CA (US);

J. Stuart Nelson, Laguna Niguel, CA (US);

Inventors:

Christopher G. Rylander, Blacksburg, VA (US);

Thomas E. Milner, Austin, TX (US);

Oliver Stumpp, Palo Alto, CA (US);

J. Stuart Nelson, Laguna Niguel, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G02C 7/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Embodiments of the present disclosure provides systems, devices, and methods for non-invasively modifying, maintaining, or controlling local tissue optical properties. Methods and devices of the disclosure may be used for optically clearing tissue, for example, for diagnostic and/or therapeutic purposes. A method of optically clearing a tissue may comprise contacting the tissue with an optical clearing device having a base, an array of pins fixed to one side of the base, a brim fixed to the base, an inlet port in the base, an exit port in the base, and a handpiece interface tab fixed to the side of the base opposite the array of pins, applying a mechanical force to the tissue, and illuminating said tissue with at least one wavelength of light through the optical clearing device. A method may further comprise controlling the temperature of the tissue illuminated.


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