The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2012

Filed:

Jan. 15, 2010
Applicants:

Carlos Alemparte-gallardo, Research Triangle Park, NC (US);

David Barros-aguirre, Research Triangle Park, NC (US);

Monica Cacho-izquierdo, Research Triangle Park, NC (US);

Jose Maria Fiandor Roman, Research Triangle Park, NC (US);

Jose Luis Lavandera Diaz, Research Triangle Park, NC (US);

Modesto Jesús Remuiñan-blanco, Research Triangle Park, NC (US);

Inventors:

Carlos Alemparte-Gallardo, Research Triangle Park, NC (US);

David Barros-Aguirre, Research Triangle Park, NC (US);

Monica Cacho-Izquierdo, Research Triangle Park, NC (US);

Jose Maria Fiandor Roman, Research Triangle Park, NC (US);

Jose Luis Lavandera Diaz, Research Triangle Park, NC (US);

Modesto Jesús Remuiñan-Blanco, Research Triangle Park, NC (US);

Assignee:

Glaxo Group Limited, Greenford, Middlesex, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 471/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula (I), wherein substituents R, Rand Rare as defined, and Ar represents substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl substituted by a hydroxyalkyl substituent and an optional other substituent; compositions containing them, their use in therapy, including their use as antibacterials, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.


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