The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
Oct. 27, 2006
Masaya Kokubo, Mishima-gun, JP;
Motoyuki Tanaka, Mishima-gun, JP;
Hiroshi Ochiai, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Shiro Shibayama, Tsukuba, JP;
Masaya Kokubo, Mishima-gun, JP;
Motoyuki Tanaka, Mishima-gun, JP;
Hiroshi Ochiai, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Shiro Shibayama, Tsukuba, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
The present invention relates to a compound represented by formula (I): wherein all symbols are as defined here, a salt thereof, a solvate thereof, or a prodrug thereof. The compound of the present invention has an antagonistic activity against CXCR4 and is therefore useful as a preventive and/or therapeutic agent for CXCR4-mediated diseases, for example, inflammatory and immune diseases (for example, rheumatoid arthritis, arthritis, retinopathy, pulmonary fibrosis, rejection of transplanted organ, etc.), allergic diseases, infections (for example, human immunodeficiency virus infection, acquired immunodeficiency syndrome, etc.), psychoneurotic diseases, cerebral diseases, cardiovascular disease, metabolic diseases, and cancerous diseases (for example, cancer, cancer metastasis, etc.), or an agent for regeneration therapy.