The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
Aug. 10, 2007
Andrew Lynn, Cambridge, GB;
William Bonfield, Cambridge, GB;
Zachary D. Wissner-gross, Cambridge, MA (US);
Brendan A. Harley, Cambridge, MA (US);
Ioannis V. Yannas, Cambridge, MA (US);
Lorna J. Gibson, Cambridge, MA (US);
Andrew Lynn, Cambridge, GB;
William Bonfield, Cambridge, GB;
Zachary D. Wissner-Gross, Cambridge, MA (US);
Brendan A. Harley, Cambridge, MA (US);
Ioannis V. Yannas, Cambridge, MA (US);
Lorna J. Gibson, Cambridge, MA (US);
Cambridge Enterprise Limited, Cambridge, GB;
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
A process for the preparation of a composite biomaterial comprising: providing a first substantially solid component comprising one or more of collagen, a glycosaminoglycan, albumin, hyaluronan, chitosan, and synthetic polypeptides comprising a portion of the polypeptide sequence of collagen, and optionally an inorganic material, said component having at least a surface portion that is porous; providing a fluid composition comprising one or more of collagen, a glycosaminoglycan, albumin, hyaluronan, chitosan, and synthetic polypeptides comprising a portion of the polypeptide sequence of collagen, and a liquid carrier, and optionally an inorganic material; contacting said fluid composition with said porous surface portion of said first component; cooling said fluid composition to a temperature at which the liquid carrier transforms into a plurality of solid crystals or particles; removing at least some of the plurality of solid crystals or particles by sublimation and/or evaporation.