The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8318795 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 27, 2012

Filed:

Feb. 29, 2008
Applicants:

John S. Yu, Los Angeles, CA (US);

Bong Seop Lee, Torrance, CA (US);

Inventors:

John S. Yu, Los Angeles, CA (US);

Bong Seop Lee, Torrance, CA (US);

Assignee:

Cedars-Sinai Medical Center, Los Angeles, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/385 (2006.01); C07D 339/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention describes polymers containing 1,2-dithiolanes capable of acting as scavengers of free radicals, metals and reactive oxygen species. Also described are methods of synthesizing the antioxidant 1,2-dithiolane derivatives and polymerization thereof to produce biodegradable antioxidant polymers. The antioxidant polymers of the present invention may be used to treat diseases or conditions caused by oxidative stress and other free radical mediated conditions. The antioxidant polymers may also be used for the preparation of antioxidant particulate delivery devices of therapeutic agents.


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