The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
Jul. 25, 2008
Gaston Stanislas Marcella Diels, Ravels, BE;
Peter Ten Holte, Beerse, BE;
Eddy Jean Edgard Freyne, Rumst, BE;
Thierry Andre Regis Grand-perret, Brussels, BE;
Kristof Van Emelen, Sint-Niklaas, BE;
Werner Constant Johan Embrechts, Oud-Turnhout, BE;
Pascal Ghislain André Bonnet, Berchem, BE;
Gaston Stanislas Marcella Diels, Ravels, BE;
Peter Ten Holte, Beerse, BE;
Eddy Jean Edgard Freyne, Rumst, BE;
Thierry Andre Regis Grand-Perret, Brussels, BE;
Kristof Van Emelen, Sint-Niklaas, BE;
Werner Constant Johan Embrechts, Oud-Turnhout, BE;
Pascal Ghislain André Bonnet, Berchem, BE;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to compounds or pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to compounds that are polo-like kinase (PLKs) inhibitors useful for the treatment of disease states mediated by PLK, especially PLK4, in particular such compounds that are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis.