The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2012

Filed:

Feb. 21, 2011
Applicants:

Jong-min Lee, Gyeonggi-Do, KR;

Dae-wook Kim, Hawthorne, FL (US);

Young-doo Jun, Seoul, KR;

Seong-guen OH, Hawthorne, FL (US);

Christopher Paradies, Tampa, FL (US);

Inventors:

Jong-Min Lee, Gyeonggi-Do, KR;

Dae-Wook Kim, Hawthorne, FL (US);

Young-Doo Jun, Seoul, KR;

Seong-Guen Oh, Hawthorne, FL (US);

Christopher Paradies, Tampa, FL (US);

Assignee:

Medical Tool & Technology LLC, Hawthorne, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/695 (2006.01); A61K 31/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

Size-controlled immobilization of metal nano-clusters onto particles or nanoparticles is achieved using a polyol process. Polyol processing makes it possible to use thiol groups as a chemical protocol to functionalize the surface of particles, such as silica and polystyrene nanoparticles. Metal nano-clusters, such as silver, gold, platinum and palladium, nucleate and grow on the surface of the particles. The metal nano-clusters may be synthesized in a one-pot process from metal salts, nitrates, nitrites, sulfates, sulfites and the like. Any source of metal ions compatible with the polyol suspension and selected particles may be used. The size of immobilized metal nano-clusters may be controlled by additions of a poly(vinylpyrrolidone) or other polymer capable of regulating the metal ion reduction and nucleation process and by controlling concentration of metal ions, the nucleation and/or growth temperatures, and processing time.


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