The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
May. 15, 2007
Keiichi Numata, Tokyo, JP;
Noriyuki Okujo, Tokyo, JP;
Siew Eim Khor, Selangor, MY;
Lee LI Tan, Selangor, MY;
Annie George, Selangor, MY;
Szu Ting NG, Selangor, MY;
Chin Jye Tan, Selangor, MY;
Hironobu Iinuma, Tokyo, JP;
Yasuo Fukagawa, Tokyo, JP;
Kunimoto Hotta, Tokyo, JP;
Seiji Shibahara, Tokyo, JP;
Shinichi Kondo, Tokyo, JP;
Satoshi Nimura, Tokyo, JP;
Keiichi Numata, Tokyo, JP;
Noriyuki Okujo, Tokyo, JP;
Siew Eim Khor, Selangor, MY;
Lee Li Tan, Selangor, MY;
Annie George, Selangor, MY;
Szu Ting Ng, Selangor, MY;
Chin Jye Tan, Selangor, MY;
Hironobu Iinuma, Tokyo, JP;
Yasuo Fukagawa, Tokyo, JP;
Kunimoto Hotta, Tokyo, JP;
Seiji Shibahara, Tokyo, JP;
Shinichi Kondo, Tokyo, JP;
Satoshi Nimura, Tokyo, JP;
Nimura Genetic Solutions Co., Ltd., Tokyo, JP;
Forest Research Institute Malaysia, Selangor, MY;
Abstract
Seven novel antibiotic substances can be produced by cultivation of a microbial strain which has been isolated from a soil sample and which is designated assp. A 34030 (deposited under an access number FERM BP-10505 in terms of Budapest Treaty). These seven antibiotic substances are named as bispolide A1, bispolide A2, bispolide A3, bispolide B1, bispolide B2a, bispolide B2b and bispolide B3, respectively. These bispolides are each novel compounds which have a chemical structure as collectively represented by the general formula (III) shown below: These bispolides have each a high antibacterial activity against a variety of bacteria, particularly Gram-positive bacteria and their antibiotic-resistant strains, and hence these bispolides each are effective and useful for therapeutically treating bacterial infections of Gram-positive bacteria in humans and animals.