The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
Jul. 26, 2005
Teresa P. Dilorenzo, Bayside, NY (US);
Scott M. Lieberman, Philadelphia, PA (US);
David V. Serreze, Ellsworth, ME (US);
Teresa P. DiLorenzo, Bayside, NY (US);
Scott M. Lieberman, Philadelphia, PA (US);
David V. Serreze, Ellsworth, ME (US);
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
The Jackson Laboratory, Bar Harbor, ME (US);
Abstract
Provided are oligopeptide antigens to AI4-like T cells, and mouse proteins comprising those antigens. The oligopeptide antigens comprise the amino acid sequence XX(I/D/F/L)ENY(I/L)(E/W/Y)(L/M) or VMLENYTHL. Additionally provided are methods for treating a mammal having or at risk for type 1 diabetes using these antigens, or compounds which reduce or eliminate expression of these antigens. Kits comprising these antigens, and methods for determining whether a mammal is at risk for or has type 1 diabetes are also provided.