The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
Mar. 05, 2008
Stefano Fazioni, Meda, IT;
Keith Hovda, Kent, WA (US);
Valeria Livi, Sesto San Giovanni, IT;
Marc Mckennon, Seattle, WA (US);
Luigi Siviero, Vimercate, IT;
Holly Spoonemore, Bellevue, WA (US);
Stefano Fazioni, Meda, IT;
Keith Hovda, Kent, WA (US);
Valeria Livi, Sesto San Giovanni, IT;
Marc McKennon, Seattle, WA (US);
Luigi Siviero, Vimercate, IT;
Holly Spoonemore, Bellevue, WA (US);
Cell Therapeutics, Inc., Seattle, WA (US);
Abstract
The invention relates to a method for determining the amount of conjugated taxane, in particular paclitaxel, in a PGA-taxane conjugate said method comprising: a) reacting the PGA-taxane conjugate with a compound formula (I): RRN—NH(I), wherein Rand Rare as defined in the description; to give a unbound taxane and a PGA hydrazide and b) determining the amount of unbound taxane.