The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2012
Filed:
Nov. 29, 2006
Molly M. Stevens, London, GB;
Rein Ulijn, Glasgow, GB;
Anna Sague Laromaine, Cassà de la Selva, ES;
Liling Koh, Singapore, SG;
Molly M. Stevens, London, GB;
Rein Ulijn, Glasgow, GB;
Anna Sague Laromaine, Cassà de la Selva, ES;
Liling Koh, Singapore, SG;
Imperial Innovations Limited, London, GB;
Abstract
The present invention provides a particle aggregate comprising particles linked to other particles via linkers that are capable of being cleaved by an enzyme. The particles may be linked directly to other particles by the linkers or may be linked indirectly by means of a binding moiety. The invention also provides a particle coupled to a binding moiety via a linker that can be cleaved by an enzyme. The present invention may be used in diagnosing a disease or condition associated with the enzyme, or may be used to treat such a disease or condition whereby the drug is retained in the particle aggregate until the linkers are cleaved by the enzyme.