The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2012

Filed:

Oct. 15, 2010
Applicants:

Kevin W. Anderson, Hackettstown, NJ (US);

Paul Gillespie, Westfield, NJ (US);

Nicholas J. S. Huby, Scotch Plains, NJ (US);

Norman Kong, West Caldwell, NJ (US);

John L. Roberts, Budd Lake, NJ (US);

Pamela L. Rossman, Nutley, NJ (US);

Sung-sau SO, Verona, NJ (US);

Inventors:

Kevin W. Anderson, Hackettstown, NJ (US);

Paul Gillespie, Westfield, NJ (US);

Nicholas J. S. Huby, Scotch Plains, NJ (US);

Norman Kong, West Caldwell, NJ (US);

John L. Roberts, Budd Lake, NJ (US);

Pamela L. Rossman, Nutley, NJ (US);

Sung-Sau So, Verona, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 285/01 (2006.01); C07D 417/06 (2006.01); A61K 31/425 (2006.01); A61K 31/4535 (2006.01); A61K 31/4523 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds according to formula 1, which exhibit cytotoxic activity. The compounds may be used in the treatment of cancer.


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