The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2012

Filed:

Oct. 23, 2009
Applicants:

Zita Mendes, Lisbon, PT;

António Carlos Silva Henriques, Forte da Casa, PT;

William Heggie, Cabanas, PT;

Inventors:

Zita Mendes, Lisbon, PT;

António Carlos Silva Henriques, Forte da Casa, PT;

William Heggie, Cabanas, PT;

Assignee:

Merial Limited, Duluth, GA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/00 (2006.01); C07G 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods for synthesizing macrolide compounds which are known to have antibacterial activity, and are useful in the therapy of bacterial infections in mammals. More specifically, the invention relates to methods for synthesizing the macrolide antibiotic, gamithromycin utilizing a novel configuration of catalysts, chemical structures, and/or methods. An embodiment of the present invention may include allowing multiple chemical reactions to proceed without the isolation of chemical intermediates. Thus, multiple reactions may occur in one reaction vessel allowing for a considerable decrease in the cycle-time. The present invention also provides a novel method for inhibiting degradation while isolating a structure of a pharmaceutical composition.


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