The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2012

Filed:

Dec. 12, 2008
Applicants:

Sudha Rajamani, Cambridge, MA (US);

Felix Olasagasti, Santa Cruz, CA (US);

David W. Deamer, Santa Cruz, CA (US);

Seico Benner, Santa Cruz, CA (US);

Inventors:

Sudha Rajamani, Cambridge, MA (US);

Felix Olasagasti, Santa Cruz, CA (US);

David W. Deamer, Santa Cruz, CA (US);

Seico Benner, Santa Cruz, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/00 (2006.01); C07H 21/00 (2006.01); C07K 1/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention herein disclosed provides for methods for the synthesis of polymers from monomers. In particular the method provides for the synthesis of polynucleotides from mononucleotides in the absence of catalytic enzymes. The method comprises providing an aqueous solution having a plurality of phospholipid molecules and monomer molecules; subjecting the aqueous solution to fluctuating temperature conditions; subjecting the aqueous solution to fluctuating cycles of drying and hydrating conditions; subjecting the aqueous solution to fluctuating [H] conditions; the fluctuating conditions thereby allowing formation of a chemical bond between at least two monomers to create a polymer. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.


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