The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2012
Filed:
Jun. 18, 2008
Applicants:
Daumantas Matulis, Vilnius, LT;
Inga Cikotiene, Vilnius, LT;
Egidijus Kazlauskas, Vilnius, LT;
Jurgita Matuliene, Vilnius, LT;
Inventors:
Daumantas Matulis, Vilnius, LT;
Inga Cikotiene, Vilnius, LT;
Egidijus Kazlauskas, Vilnius, LT;
Jurgita Matuliene, Vilnius, LT;
Assignee:
Biotechnologijos Institutas, , LT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/433 (2006.01); C07D 285/06 (2006.01); C07C 243/18 (2006.01);
U.S. Cl.
CPC ...
Abstract
Invention is related to novel compounds -5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles with general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit Hsp90 chaperone which participate in cancer progression. This invention is also related to new intermediate compounds which are used for the synthesis of thiadiazoles of general formula (I).