The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2012
Filed:
Sep. 19, 2008
Liping H. Pettus, Thousand Oaks, CA (US);
Kelvin K. C. Sham, Thousand Oaks, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Shimin Xu, San Diego, CA (US);
Liping H. Pettus, Thousand Oaks, CA (US);
Kelvin K. C. Sham, Thousand Oaks, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Shimin Xu, San Diego, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention comprises a new class of compounds useful for modulating the activity of p38 MAP kinase. The compounds have a general Formula I wherein A, A, A, A, A, A, Rand Rare defined herein. The invention further provides pharmaceutical compositions including one or more compounds of Formula I, use of such compounds and compositions for treatment of p38 MAP kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammatory disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.