The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2012

Filed:

Feb. 15, 2008
Applicants:

Brian K. Albrecht, Cambridge, MA (US);

Steven Bellon, Wellesley, MA (US);

Shon Booker, Thousand Oaks, CA (US);

Alan C. Cheng, Cambridge, MA (US);

Derin D'amico, Newbury Park, CA (US);

Noel D'angelo, Thousand Oaks, CA (US);

Jean-christophe Harmange, Andover, MA (US);

Tae-seong Kim, Thousand Oaks, CA (US);

Longbin Liu, Thousand Oaks, CA (US);

Mark H. Norman, Thousand Oaks, CA (US);

Aaron C. Siegmund, Ventura, CA (US);

Markian Stec, Moorpark, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Kevin Yang, San Gabriel, CA (US);

Inventors:

Brian K. Albrecht, Cambridge, MA (US);

Steven Bellon, Wellesley, MA (US);

Shon Booker, Thousand Oaks, CA (US);

Alan C. Cheng, Cambridge, MA (US);

Derin D'Amico, Newbury Park, CA (US);

Noel D'Angelo, Thousand Oaks, CA (US);

Jean-Christophe Harmange, Andover, MA (US);

Tae-Seong Kim, Thousand Oaks, CA (US);

Longbin Liu, Thousand Oaks, CA (US);

Mark H. Norman, Thousand Oaks, CA (US);

Aaron C. Siegmund, Ventura, CA (US);

Markian Stec, Moorpark, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Kevin Yang, San Gabriel, CA (US);

Assignee:

Amgen Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 215/233 (2006.01); C07D 413/14 (2006.01); C07D 205/08 (2006.01); C07D 409/14 (2006.01); C07D 401/14 (2006.01); C07D 239/36 (2006.01); A61K 31/4709 (2006.01); A61K 31/5355 (2006.01); A61K 31/397 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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