The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2012

Filed:

Jul. 30, 2010
Applicants:

Leopold Grillberger, Vienna, AT;

Alexandra Spenger, Vienna, AT;

Meinhard Hasslacher, Vienna, AT;

Rana Grillberger, Vienna, AT;

Manfred Reiter, Vienna, AT;

Inventors:

Leopold Grillberger, Vienna, AT;

Alexandra Spenger, Vienna, AT;

Meinhard Hasslacher, Vienna, AT;

Rana Grillberger, Vienna, AT;

Manfred Reiter, Vienna, AT;

Assignees:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare S.A., Glattpark (Opfikon), CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 9/00 (2006.01); C12N 9/50 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides culture mediums that are useful for the expression of ADAMTS proteins, such as ADAMTS13. Methods for the expression and purification of ADAMTS proteins are also provided. In some embodiments, the mediums and methods of the invention are useful for the expression of ADAMTS proteins having high specific activities. Also provided are ADAMTS, e.g., ADAMTS13, protein compositions with high specific activities, which are expressed and purified according to the methods provided herein.


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