The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2012
Filed:
Mar. 02, 2007
Damien Marchal, Paris, FR;
Benoît Limoges, Bretigny-sur-Orge, FR;
Murielle Dequaire, Dijon, FR;
Universite Paris Diderot-Paris 7, Paris Cedex, FR;
Universite de Bourgogne, Dijon Cedex, FR;
Centre National de la Recherche Scientifique, Paris Cedex, FR;
Abstract
The invention relates to a method and a collection for the electrochemical detection of target nucleic acid sequences. According to the method, a biological sample that may contain a nucleic acid is provided, said nucleic acid being capable of containing a target sequence, said biological sample being mixed with an oxidizing agent, said target sequence comprising at least one nucleotide base that can be oxidized by said oxidizing agent; complementary means capable of coupling with said target sequence are provided; according to the invention, said complementary means comprise activatable amplification means suitable for replicating said target sequence, said amplification means comprising at least nucleotides which include said nucleotide base, wherein said nucleotides are able to be consumed during replication so as to constitute replicated nucleic acids; and the presence of said target sequence is determined by applying an electric field to said sample and recording the decrease in the electric current.