The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8309599 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 13, 2012

Filed:

Sep. 15, 2010
Applicants:

Kazunori Koide, Pittsburgh, PA (US);

Brian J. Albert, Pittsburgh, PA (US);

Ananthapadmanabhan Sivaramakrishnan, Jamestown, NC (US);

Inventors:

Kazunori Koide, Pittsburgh, PA (US);

Brian J. Albert, Pittsburgh, PA (US);

Ananthapadmanabhan Sivaramakrishnan, Jamestown, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/35 (2006.01); C07D 315/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.


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