The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2012

Filed:

Jun. 26, 2008
Applicants:

Stefanie Flohr, Lörrach, DE;

Stefan Andreas Randl, Basel, CH;

Nils Ostermann, Binzen, DE;

Ulrich Hassiepen, Lörrach, DE;

Frederic Berst, Altkirch, FR;

Ursula Bodendorf, Basel, CH;

Bernd Gerhartz, Lörrach, DE;

Andreas Marzinzik, Weil, DE;

Claus Ehrhardt, Lörrach, DE;

Josef Gottfried Meingassner, Vienna, AT;

Inventors:

Stefanie Flohr, Lörrach, DE;

Stefan Andreas Randl, Basel, CH;

Nils Ostermann, Binzen, DE;

Ulrich Hassiepen, Lörrach, DE;

Frederic Berst, Altkirch, FR;

Ursula Bodendorf, Basel, CH;

Bernd Gerhartz, Lörrach, DE;

Andreas Marzinzik, Weil, DE;

Claus Ehrhardt, Lörrach, DE;

Josef Gottfried Meingassner, Vienna, AT;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/496 (2006.01); A61K 31/454 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/404 (2006.01); A61K 31/4035 (2006.01); A61K 31/403 (2006.01); A61K 31/4025 (2006.01); A61K 31/40 (2006.01); C07D 413/12 (2006.01); C07D 409/12 (2006.01); C07D 405/12 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 217/26 (2006.01); C07D 211/60 (2006.01); C07D 209/42 (2006.01); C07D 209/44 (2006.01); C07D 209/52 (2006.01); C07D 207/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.


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