The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2012
Filed:
May. 19, 2010
Daniel Marquess, Half Moon Bay, CA (US);
Paul R. Fatheree, San Francisco, CA (US);
S. Derek Turner, San Francisco, CA (US);
Daniel D. Long, San Francisco, CA (US);
Seok-ki Choi, Palo Alto, CA (US);
Adam A. Goldblum, San Francisco, CA (US);
Daniel Genov, San Francisco, CA (US);
Daniel Marquess, Half Moon Bay, CA (US);
Paul R. Fatheree, San Francisco, CA (US);
S. Derek Turner, San Francisco, CA (US);
Daniel D. Long, San Francisco, CA (US);
Seok-ki Choi, Palo Alto, CA (US);
Adam A. Goldblum, San Francisco, CA (US);
Daniel Genov, San Francisco, CA (US);
Theravance, Inc., South San Francisco, CA (US);
Abstract
The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds of Formula (I). The invention also provides pharmaceutical compositions comprising such compounds, the use such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds. Wherein; Ris hydrogen, halo, hydroxy, Calkyl, or Calkoxy; Ris Calkyl, or Ccycloalkyl; Ris hydrogen or Calkyl: Ris S(O)Ror C(O)R; Ris hydrogen, Calkyl, Calkyl substituted with —OH or Calkoxy, or —CH-pyrydyl; Ris Calkyl; or Rand Rtaken together from Calkylenyl; and Ris hydrogen, Calkyl, or pyrydyl; or pharmaceutically-acceptable salt or solvate or stereoisomer thereof.