The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2012
Filed:
Aug. 08, 2008
Masakazu Fujio, Osaka, JP;
Toshihiko Tanaka, Osaka, JP;
Hisao Takayanagi, Osaka, JP;
Hiroyuki Satoh, Osaka, JP;
Takanori Ito, Osaka, JP;
Masakazu Fujio, Osaka, JP;
Toshihiko Tanaka, Osaka, JP;
Hisao Takayanagi, Osaka, JP;
Hiroyuki Satoh, Osaka, JP;
Takanori Ito, Osaka, JP;
Mitsubishi Tanabe Pharma Corporation, Osaka-shi, JP;
Abstract
The invention provides a salt of (R)-3-[2-(2-hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one and a crystal thereof. (R)-3-[2-(2-Hydroxymethylpyrrolidin-1-ypethyl]-5-methyl-2H-1-isoquinolin-1-one monophosphate is a compound which is chemically stable, has high solubility, and shows less weight change due to humidity as compared to a free form and monohydrochloride dihydrate, and is superior as a bulk drug for pharmaceutical products.