The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2012

Filed:

Mar. 26, 2008
Applicants:

Hope Hart, Research Triangle Park, NC (US);

Jeng S. Chen, Research Triangle Park, NC (US);

Cheryl Stacy, Research Triangle Park, NC (US);

Frederick Walters, Research Triangle Park, NC (US);

Inventors:

Hope Hart, Research Triangle Park, NC (US);

Jeng S. Chen, Research Triangle Park, NC (US);

Cheryl Stacy, Research Triangle Park, NC (US);

Frederick Walters, Research Triangle Park, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/325 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different(Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.


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