The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2012
Filed:
Apr. 10, 2009
Applicants:
Krys Bankiewicz, Garrett Park, MD (US);
Janet Cunningham, Alameda, CA (US);
Inventors:
Krys Bankiewicz, Garrett Park, MD (US);
Janet Cunningham, Alameda, CA (US);
Assignees:
Genzyme Corporation, Framingham, MA (US);
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 5/00 (2006.01); A01N 63/00 (2006.01); A01N 43/04 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods of delivering viral vectors, particularly recombinant AAV virions, to the central nervous system (CNS) are provided for the treatment of CNS disorders, particularly those disorders which involve the neurotransmitter dopamine. The methods entail providing rAAV virions that comprise a transgene encoding aromatic amino acid decarboxylase (AADC) and administering the virions to the brain of a mammal using a non-manual pump.