The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2012
Filed:
Dec. 14, 2009
Jen-kun Chen, Hsinchu, TW;
Jinn-jer Peir, Hsinchu, TW;
Mei-ya Wang, Taoyuan, TW;
Chih-hui Liu, Pingtung, TW;
Fong-in Chou, Hsinchu, TW;
Chung-shi Yang, Taichung, TW;
Mo-hsiung Yang, Hsinchu County, TW;
Mei-hui Shih, Taichung, TW;
Jen-Kun Chen, Hsinchu, TW;
Jinn-Jer Peir, Hsinchu, TW;
Mei-Ya Wang, Taoyuan, TW;
Chih-Hui Liu, Pingtung, TW;
Fong-In Chou, Hsinchu, TW;
Chung-Shi Yang, Taichung, TW;
Mo-Hsiung Yang, Hsinchu County, TW;
Mei-Hui Shih, Taichung, TW;
National Health Research Institutes, Miaoli County, TW;
National Tsing Hua University, Hsinchu, TW;
Abstract
Methods of preparing a composition comprising non-ionic, radioactive gold nanoparticles (R-GNPs) are disclosed. The method comprises: a) providing an aqueous composition comprising gold (Au-197) ions in the absence of a template; and b) exposing the aqueous composition in the absence of the template to neutron irradiation to generate the composition comprising the non-ionic R-GNPs. Alternatively, the method comprises: a) providing an aqueous composition comprising gold (Au-197) nanoparticles (GNPs) in the absence of a template; and b) exposing the aqueous composition comprising the GNPs in the absence of the template to neutron irradiation and thereby generating the composition comprising the non-ionic R-GNPs. Compositions that comprises mesoporous silica nanoparticles (MSNs) and non-ionic R-GNPs encapsulated within pores and/or channels and further anchored to the surfaces of the MSNs, and methods of making the same are also disclosed.