The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2012

Filed:

Mar. 05, 2010
Applicants:

Jean Gudas, Los Angeles, CA (US);

Aya Jakobovits, Beverly Hills, CA (US);

Zili an, Santa Monica, CA (US);

Robert Kendall Morrison, Santa Monica, CA (US);

Karen Jane Meyrick Morrison, Santa Monica, CA (US);

Xiao-chi Jia, Los Angeles, CA (US);

Dennis Benjamin, Redmond, WA (US);

Ruth Moser, Bellevue, WA (US);

Peter Senter, Seattle, WA (US);

Inventors:

Jean Gudas, Los Angeles, CA (US);

Aya Jakobovits, Beverly Hills, CA (US);

Zili An, Santa Monica, CA (US);

Robert Kendall Morrison, Santa Monica, CA (US);

Karen Jane Meyrick Morrison, Santa Monica, CA (US);

Xiao-chi Jia, Los Angeles, CA (US);

Dennis Benjamin, Redmond, WA (US);

Ruth Moser, Bellevue, WA (US);

Peter Senter, Seattle, WA (US);

Assignee:

Agensys, Inc., Santa Monica, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.


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