The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2012

Filed:

Oct. 23, 2008
Applicants:

Keizo Sugasawa, Tokyo, JP;

Kenichi Kawaguchi, Tokyo, JP;

Takaho Nomura, Tokyo, JP;

Shunichiro Matsumoto, Tokyo, JP;

Takashi Shin, Tokyo, JP;

Hidenori Azami, Tokyo, JP;

Tomoaki Abe, Tokyo, JP;

Akira Suga, Tokyo, JP;

Ryushi Seo, Tokyo, JP;

Masayuki Tanahashi, Tokyo, JP;

Toru Watanabe, Tokyo, JP;

Inventors:

Keizo Sugasawa, Tokyo, JP;

Kenichi Kawaguchi, Tokyo, JP;

Takaho Nomura, Tokyo, JP;

Shunichiro Matsumoto, Tokyo, JP;

Takashi Shin, Tokyo, JP;

Hidenori Azami, Tokyo, JP;

Tomoaki Abe, Tokyo, JP;

Akira Suga, Tokyo, JP;

Ryushi Seo, Tokyo, JP;

Masayuki Tanahashi, Tokyo, JP;

Toru Watanabe, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/68 (2006.01); C07D 221/20 (2006.01); C07D 491/20 (2006.01); C07D 413/14 (2006.01); C07D 239/09 (2006.01); A61K 31/535 (2006.01); A61K 31/505 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
Abstract

[Object] To provide a therapeutic and/or prophylactic agent for urinary frequency, urinary urgency, and urinary incontinence associated with various lower urinary tract diseases including overactive bladder, various lower urinary tract diseases accompanied by lower urinary tract pain, such as interstitial cystitis, chronic prostatitis, and the like, and various diseases accompanied by pain, based on an excellent trkA receptor inhibitory action. [Means for Solution] A novel azolecarboxamide compound in which a thiazole ring or an oxazole ring is bonded to a benzene ring, a pyridine ring, a pyridazine ring, a thiophene ring, a pyrazole ring or a pyrrole ring through carboxamide, or a salt thereof is confirmed to have a potent trkA receptor inhibitory activity, and found to be capable of being used as a therapeutic and/or prophylactic agent which is excellent in efficacy and safety for urinary frequency, urinary urgency, and urinary incontinence associated with various lower urinary tract diseases including overactive bladder, various lower urinary tract diseases accompanied by lower urinary tract pain, such as interstitial cystitis, chronic prostatitis, and the like, and various diseases accompanied by pain, thereby completing the present invention.


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