The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2012
Filed:
Jun. 29, 2011
Antoni Kozlowski, Huntsville, AL (US);
Remy F. Gross, Iii, Petaluma, CA (US);
Samuel P. Mcmanus, Huntsville, AL (US);
Antoni Kozlowski, Huntsville, AL (US);
Remy F. Gross, III, Petaluma, CA (US);
Samuel P. McManus, Huntsville, AL (US);
Nektar Therapeutics, San Francisco, CA (US);
Abstract
The present invention is directed a method comprising administering a composition to an individual, wherein the composition comprises a plurality of conjugates, each conjugate in the plurality a protein derivatized with a water-soluble polymer, wherein the polymer is coupled to the protein via succinimide groups covalently attached to either cysteine sulfhydryl groups or lysine amino groups, and substantially all of the succinimide groups present in the composition are present in a ring-opened form.