The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2012
Filed:
Feb. 14, 2011
Bansi Lal, Mumbai, IN;
Kalpana Joshi, Thane, IN;
Sanjeev Kulkarni, Mumbai, IN;
Malcolm Mascarenhas, Mumbai, IN;
Shrikant Kamble, Mumbai, IN;
Maggie Joyce Rathos, Thane, IN;
Rajendrakumar Joshi, Mumbai, IN;
Bansi Lal, Mumbai, IN;
Kalpana Joshi, Thane, IN;
Sanjeev Kulkarni, Mumbai, IN;
Malcolm Mascarenhas, Mumbai, IN;
Shrikant Kamble, Mumbai, IN;
Maggie Joyce Rathos, Thane, IN;
Rajendrakumar Joshi, Mumbai, IN;
Piramal Healthcare Limited, Mumbai, IN;
Abstract
The present invention relates to novel compounds for the inhibition of cyclin-dependent kinases, and more particularly, to chromenone derivatives of formula (Ia), wherein R, R, R, R, R, R, Rand A have the meanings indicated in the claims. The invention also relates to processes for the preparation of the compounds of formula (Ia), to methods of inhibiting cyclin-dependent kinases and of inhibiting cell proliferation, to the use of the compounds of formula (Ia) in the treatment and prophylaxis of diseases, which can be treated or prevented by the inhibition of cyclin-dependent kinases such as cancer, to the use of the compounds of formula (Ia) in the preparation of medicaments to be applied in such diseases. The invention further relates to compositions containing a compound of formula (Ia) either alone or in combination with another active agent, in admixture or otherwise in association with an inert carrier, in particular pharmaceutical compositions containing a compound of formula (Ia) either alone or in combination with another active agent, together with pharmaceutically acceptable carrier substances and auxiliary substances.