The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2012
Filed:
Apr. 20, 2007
Peter Abraham Christiaan 't Hoen, Leiden, NL;
Petronella Johanna Elisabeth Sterrenburg, Voorhout, NL;
Johannes Theodorus Den Dunnen, Rotterdam, NL;
Garrit Jan Boudewijn Van Ommen, Amsterdam, NL;
Peter Abraham Christiaan 't Hoen, Leiden, NL;
Petronella Johanna Elisabeth Sterrenburg, Voorhout, NL;
Johannes Theodorus den Dunnen, Rotterdam, NL;
Garrit Jan Boudewijn van Ommen, Amsterdam, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Abstract
The present invention provides means and methods for alleviating genetic disease. A genetic defect that has a phenotype in differentiated cells can lead to defects in precursor cells thereof. These so-called secondary defects contribute to the overall disease of the individual. In the present invention, genetic intervention with the aim to alleviate symptoms of genetic disease is directed toward the primary genetic defect in the differentiated cell and the secondary defect in the precursor cell.