The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2012

Filed:

Jun. 22, 2007
Applicants:

Thomas P. J. Garrett, Brunswick, AU;

Timothy Edward Adams, Lower Plenty, AU;

George Lovrecz, Balwyn North, AU;

Neil Moreton Mckern, Lilydale, AU;

Michael Colin Lawrence, Newport, AU;

Lindsay Gale Sparrow, Canterbury, AU;

Colin Wesley Ward, Carlton North, AU;

Meizhen Lou, Scoresby, AU;

Victor Strelstov, Templestowe, AU;

Inventors:

Thomas P. J. Garrett, Brunswick, AU;

Timothy Edward Adams, Lower Plenty, AU;

George Lovrecz, Balwyn North, AU;

Neil Moreton McKern, Lilydale, AU;

Michael Colin Lawrence, Newport, AU;

Lindsay Gale Sparrow, Canterbury, AU;

Colin Wesley Ward, Carlton North, AU;

Meizhen Lou, Scoresby, AU;

Victor Strelstov, Templestowe, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); G01N 33/00 (2006.01); G01N 23/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the crystal structure of the insulin receptor ectodomain, to the nature of its N-linked glycans and to methods of using the crystal and related structural information to screen for and design compounds that interact with or modulate the insulin receptor and/or the closely-related insulin-like growth factor receptors or variants thereof.


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