The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2012
Filed:
Sep. 05, 2008
Chiang Jia LI, Cambridge, MA (US);
Ji-feng Liu, Winchester, MA (US);
Youzhi LI, Westwood, MA (US);
Wei LI, Wayland, MA (US);
Harry Rogoff, Wrentham, MA (US);
Chiang Jia Li, Cambridge, MA (US);
Ji-Feng Liu, Winchester, MA (US);
Youzhi Li, Westwood, MA (US);
Wei Li, Wayland, MA (US);
Harry Rogoff, Wrentham, MA (US);
Boston Biomedical, Inc., Norwood, MA (US);
Abstract
The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof.