The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2012

Filed:

Dec. 11, 2009
Applicants:

Kazuhiro Ito, London, GB;

Peter Strong, London, GB;

William Garth Rapeport, London, GB;

Peter John Murray, London, GB;

John King-underwood, Pendock, GB;

Jonathan Gareth Williams, Nottingham, GB;

Stuart Thomas Onions, Nottingham, GB;

Kevin Joly, Nottingham, GB;

Catherine Elisabeth Charron, London, GB;

Inventors:

Kazuhiro Ito, London, GB;

Peter Strong, London, GB;

William Garth Rapeport, London, GB;

Peter John Murray, London, GB;

John King-Underwood, Pendock, GB;

Jonathan Gareth Williams, Nottingham, GB;

Stuart Thomas Onions, Nottingham, GB;

Kevin Joly, Nottingham, GB;

Catherine Elisabeth Charron, London, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/505 (2006.01); A61K 31/445 (2006.01); A61K 31/4427 (2006.01); C07D 413/14 (2006.01); C07D 403/02 (2006.01); C07D 213/02 (2006.01); C07D 211/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure relates to compounds of formula (I): which are inhibitors of p38 mitogen-activated protein kinase enzymes, particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.


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