The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2012

Filed:

Dec. 11, 2009
Applicants:

Kazuhiro Ito, London, GB;

Peter Strong, London, GB;

William Garth Rapeport, London, GB;

Peter John Murray, London, GB;

John King-underwood, Pendock, GB;

Jonathan Gareth Williams, Nottingham, GB;

Stuart Thomas Onions, Nottingham, GB;

Simon Christopher Hirst, Nottingham, GB;

David Michel Adrien Taddei, Nottingham, GB;

Catherine Elisabeth Charron, London, GB;

Inventors:

Kazuhiro Ito, London, GB;

Peter Strong, London, GB;

William Garth Rapeport, London, GB;

Peter John Murray, London, GB;

John King-Underwood, Pendock, GB;

Jonathan Gareth Williams, Nottingham, GB;

Stuart Thomas Onions, Nottingham, GB;

Simon Christopher Hirst, Nottingham, GB;

David Michel Adrien Taddei, Nottingham, GB;

Catherine Elisabeth Charron, London, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/505 (2006.01); A61K 31/445 (2006.01); A61K 31/4427 (2006.01); A61K 31/496 (2006.01); C07D 413/14 (2006.01); C07D 403/02 (2006.01); C07D 213/02 (2006.01); C07D 211/06 (2006.01); C07D 401/02 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof, which are inhibitors of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.


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