The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2012

Filed:

Nov. 16, 2007
Applicants:

Michael B. Sporn, Tunbridge, VT (US);

Karen T. Liby, West Lebanon, NH (US);

Tadashi Honda, Hanover, NH (US);

Gregory Mundy, San Antonio, TX (US);

Ross Garrett, Austin, TX (US);

Hari Reddi, El Macero, CA (US);

Gordon W. Gribble, Lebanon, NH (US);

Takahiro Niikura, Kobe, JP;

Inventors:

Michael B. Sporn, Tunbridge, VT (US);

Karen T. Liby, West Lebanon, NH (US);

Tadashi Honda, Hanover, NH (US);

Gregory Mundy, San Antonio, TX (US);

Ross Garrett, Austin, TX (US);

Hari Reddi, El Macero, CA (US);

Gordon W. Gribble, Lebanon, NH (US);

Takahiro Niikura, Kobe, JP;

Assignees:

Trustees of Dartmouth College, Hanover, NH (US);

Osteoscreen, Inc., San Antonio, TX (US);

The Regents of the Universtiy of California, Oakland, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns methods for stimulating the growth and repair of bone and cartilage using synthetic triterpenoids and tricyclic-bis-enones. Examples of suitable triterpenoids include CDDO, CDDO-Me, CDDO-Im, and CDDO-Ethylamide. Examples of tricyclic-bis-enones include TBE-31 and TBE-34.


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