The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2012

Filed:

Aug. 25, 2004
Applicants:

George Tachas, Melbourne, AU;

Kenneth W Dobie, Del Mar, CA (US);

Ravi Jain, Carlsbad, CA (US);

Christopher I Belyea, Melbourne, AU;

Mark a Heffernan, Melbourne, AU;

Inventors:

George Tachas, Melbourne, AU;

Kenneth W Dobie, Del Mar, CA (US);

Ravi Jain, Carlsbad, CA (US);

Christopher I Belyea, Melbourne, AU;

Mark A Heffernan, Melbourne, AU;

Assignees:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Antisense Therapeutics Limited, Toorak, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.


Find Patent Forward Citations

Loading…