The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2012

Filed:

Mar. 26, 2004
Applicants:

Gina Fischer, Væ rløse, DK;

Daniel Bar-shalom, Kokkedal, DK;

Lillian Slot, Virum, DK;

Anne-marie Lademann, Charlottenlund, DK;

Inventors:

Gina Fischer, Væ rløse, DK;

Daniel Bar-Shalom, Kokkedal, DK;

Lillian Slot, Virum, DK;

Anne-Marie Lademann, Charlottenlund, DK;

Assignee:

Egalet A/S, London, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/36 (2006.01); A61K 9/22 (2006.01); A61K 9/28 (2006.01); A61K 9/24 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

A controlled release pharmaceutical composition for oral use is provided in the form of a coated matrix composition, the matrix composition comprising i) a mixture of a first and a second polymer that have plasticizing properties and which have melting points or melting intervals of a temperature of at the most 200° C., the first polymer being selected from the group consisting of polyethylene glycols and polyethylene oxides, and the second polymer being selected form block copolymer of ethylene oxide and propylene oxide including poly(ethylene-glycol-b-(DL-lactic acid-co-glycolic acid)-b-ethylene glycol (PEG-PLGA PEG), poly((DL-lactic acid-co-glycolic acid)-g-ethylene glycol) (PLGA-g-PEG), poloxamers and polyethylene oxide-polypropylene oxide (PEO-PPO), ii) a therapeutically, prophylactically and/or diagnostically active substance, the matrix composition being provided with a coating having at least one opening exposing at one surface of said matrix, wherein the active substance is released with a substantially zero order release.


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