The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2012
Filed:
Apr. 10, 2007
Applicants:
Wolf Reik, Cambridge, GB;
Hugh Morgan, Cambridge, GB;
Chun-fung Chan, Hong Kong, HK;
Inventors:
Assignee:
CellCentric Limited, , GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/43 (2006.01); C12N 9/88 (2006.01);
U.S. Cl.
CPC ...
Abstract
Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilizing a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy.