The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2012
Filed:
Dec. 04, 2008
Norihiko Okochi, Tokyo, JP;
Norihiko Okochi, Tokyo, JP;
Dai Nippon Printing Co., Ltd., Tokyo, JP;
Abstract
The object of the present invention is to inexpensively produce a carrier having a hydrophilic spacer, for immobilizing biological materials, etc., which has been very expensive so far. The present invention relates to a method of producing a substance immobilizing carrier, in which carboxyl groups or active ester groups are positioned on a support, which is characterized by including: a functional group-introducing step in which a functional group is introduced on a surface of a support; a hydrophilic compound binding step in which a hydrophilic compound having a binding group that can bind with the functional group and a hydroxyl group, is bound to the functional group through binding between the functional group and the binding group; a carboxyl group-forming step in which a carboxyl group is formed through ring-opening half-esterification between a cyclic acid anhydride and a hydroxyl group on the bound hydrophilic compound; and, if necessary, an active esterification step in which the carboxyl group formed in the carboxyl group forming step is converted into an active ester.