The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2012
Filed:
May. 01, 2009
Brian Nicholas Cook, Danbury, CT (US);
Christian Harcken, New Milford, CT (US);
Thomas Wei-ho Lee, Lexington, MA (US);
Pingrong Liu, Southbury, CT (US);
Jord Lord, Poughkeepsie, NY (US);
Can Mao, New Milford, CT (US);
Wang Mao, Milford, CT (US);
Brian Christopher Raudenbush, Beacon Falls, CT (US);
Hossein Razavi, Danbury, CT (US);
Christopher Ronald Sarko, New Milford, CT (US);
Alen David Swinamer, Woodbury, CT (US);
Brian Nicholas Cook, Danbury, CT (US);
Christian Harcken, New Milford, CT (US);
Thomas Wei-Ho Lee, Lexington, MA (US);
Pingrong Liu, Southbury, CT (US);
Jord Lord, Poughkeepsie, NY (US);
Can Mao, New Milford, CT (US);
Wang Mao, Milford, CT (US);
Brian Christopher Raudenbush, Beacon Falls, CT (US);
Hossein Razavi, Danbury, CT (US);
Christopher Ronald Sarko, New Milford, CT (US);
Alen David Swinamer, Woodbury, CT (US);
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
Disclosed are compounds of the formula (I) which block the interaction of CCR1 and its ligands and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.