The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2012

Filed:

Jul. 01, 2011
Applicants:

Anastasia Khvorova, Boulder, CO (US);

Angela Reynolds, Littleton, CO (US);

Devin Leake, Denver, CO (US);

William Marshall, Boulder, CO (US);

Steven Read, Denver, CO (US);

Stephen Scaringe, Lafayette, CO (US);

Inventors:

Anastasia Khvorova, Boulder, CO (US);

Angela Reynolds, Littleton, CO (US);

Devin Leake, Denver, CO (US);

William Marshall, Boulder, CO (US);

Steven Read, Denver, CO (US);

Stephen Scaringe, Lafayette, CO (US);

Assignee:

Dharmacon, Inc., Lafayette, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for BACE.


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