The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2012

Filed:

Dec. 13, 2004
Applicants:

Ethel C. Feleder, Buenos Aires, AR;

Glenn A. Meyer, Wilmington, NC (US);

Marcelo A. Ricci, Buenos Aires, AR;

Joaquina Faour, Buenos Aires, AR;

Ana C. Pastini, Buenos Aires, AR;

Marcelo F. Befumo, Buenos Aires, AR;

Inventors:

Ethel C. Feleder, Buenos Aires, AR;

Glenn A. Meyer, Wilmington, NC (US);

Marcelo A. Ricci, Buenos Aires, AR;

Joaquina Faour, Buenos Aires, AR;

Ana C. Pastini, Buenos Aires, AR;

Marcelo F. Befumo, Buenos Aires, AR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 33/02 (2006.01); A61K 31/135 (2006.01);
U.S. Cl.
CPC ...
Abstract

The osmotic devices of the present invention include a single core comprising a salt of a drug and an osmotic salt, wherein the drug salt and the osmotic salt have a common ion. The release rate of the active drug is reduced, and the release profile of the active drug is modified, from a first order release profile to a zero order, pseudo-zero order, or sigmoidal release profile, by increasing the amount of the sodium chloride in the core of the device. In one embodiment the sodium chloride is used to modify a controlled release profile to a delayed and controlled release profile.


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