The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2012
Filed:
Mar. 23, 2005
Louise D. Mccullough, Baltimore, MD (US);
Jill Sturdivant, Chapel Hill, NC (US);
Gabriele V. Ronnett, Baltimore, MD (US);
Louise D. McCullough, Baltimore, MD (US);
Jill Sturdivant, Chapel Hill, NC (US);
Gabriele V. Ronnett, Baltimore, MD (US);
FASgen, LLC, Baltimore, MD (US);
Johns Hopkins University, Baltimore, MD (US);
Abstract
A method of neuroprotection which comprises administration of an AMPK inhibitor to a patient who is experiencing or has experienced a stroke, the compound being an AMPK inhibitor. Treatments with these agents significantly reduce the size of infarcts, and therefore minimize the loss of brain tissue and neurons. Thus, function can be preserved after stroke or ischemic injury in the brain. Similarly, neuronal loss can be minimized in degenerative diseases that cause neuronal compromise by perturbing energy utilization and availability in neurons.