The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2012

Filed:

May. 20, 2008
Applicants:

Simon C. NG, Walnut Creek, CA (US);

Keith B. Pfister, San Ramon, CA (US);

Martin Sendzik, San Mateo, CA (US);

James Sutton, Pleasanton, CA (US);

Allan S. Wagman, Belmont, CA (US);

Marion Wiesmann, Bottmingen, CH;

Inventors:

Simon C. Ng, Walnut Creek, CA (US);

Keith B. Pfister, San Ramon, CA (US);

Martin Sendzik, San Mateo, CA (US);

James Sutton, Pleasanton, CA (US);

Allan S. Wagman, Belmont, CA (US);

Marion Wiesmann, Bottmingen, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/519 (2006.01); A61K 31/506 (2006.01); A61K 31/501 (2006.01); A61K 31/497 (2006.01); A61K 31/4745 (2006.01); A61K 31/4545 (2006.01); A61K 31/454 (2006.01); A61K 31/444 (2006.01); A61K 31/4439 (2006.01); C07D 495/04 (2006.01); C07D 487/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Benzoxazole and benzothiazole compounds and their oxides, esters, prodrugs, solvates, and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent are also disclosed. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF 1R.


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