The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2012

Filed:

Oct. 27, 2008
Applicants:

Timothy Colin Hancox, Slough, GB;

Neil Anthony Pegg, Slough, GB;

Alan John Nadin, Harlow, GB;

Stephen Price, Harlow, GB;

Inventors:

Timothy Colin Hancox, Slough, GB;

Neil Anthony Pegg, Slough, GB;

Alan John Nadin, Harlow, GB;

Stephen Price, Harlow, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Thienopyrimidines of formula (I) wherein W and Rto Rare as defined in the claims, and the pharmaceutically acceptable salts thereof are inhibitors of PI3K and are selective for the p110δ isoform, which is a class Ia PI3 kinase, over both other class Ia and class Ib kinases. The compounds may be used to treat diseases and disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.


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