The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2012

Filed:

Apr. 06, 2010
Applicants:

George Kunos, Bethesda, MD (US);

Alexandros Makriyannis, Watertown, MA (US);

Inventors:

George Kunos, Bethesda, MD (US);

Alexandros Makriyannis, Watertown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/69 (2006.01); A61K 31/10 (2006.01); A61K 317/06 (2006.01); C07F 5/02 (2006.01); C07F 9/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors). Disclosed herein are potent inhibitors of FAAH and methods for their use for treating a variety of disorder, including hypertension and cardiac hypertrophy.


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