The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2012

Filed:

Nov. 29, 2007
Applicants:

Peter Mouritzen, Jyllinge, DK;

Christian Lomholt, Frederiksberg, DK;

Søren Morgenthaler Echwald, Humlebæk, DK;

Mikkel Noerholm, Belmont, MA (US);

Inventors:

Peter Mouritzen, Jyllinge, DK;

Christian Lomholt, Frederiksberg, DK;

Søren Morgenthaler Echwald, Humlebæk, DK;

Mikkel Noerholm, Belmont, MA (US);

Assignee:

Exiqon, Vedbaek, DK;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C07H 21/04 (2006.01); C07H 19/20 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to labeling kits containing novel non-natural nucleotide monomers and to methods of making and using such compounds. The invention further relates to a method of detecting the presence of a nucleic acid, e.g., RNA, of interest in a sample, the method having the following steps: providing the sample; ligating a nucleic acid of interest with a labeling reagent according to the instant invention; providing a nucleic acid array having probes directed to the nucleic acid of interest; hybridizing the labeled nucleic acid fragments to said nucleic acid array; and determining the extent of hybridization to said probes to determine the presence of the nucleic acid of interest.


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