The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2012
Filed:
Apr. 24, 2009
Masaji Okada, Sakai, JP;
Yasushi Takamori, Tokyo, JP;
Kazuyuki Ogawa, Kawagoe, JP;
Kinya Nagata, Kawagoe, JP;
Masaji Okada, Sakai, JP;
Yasushi Takamori, Tokyo, JP;
Kazuyuki Ogawa, Kawagoe, JP;
Kinya Nagata, Kawagoe, JP;
National Hospital Organization Kinki-chuo Chest Medical center, Kita-ku, Sakai, Osaka, JP;
Other;
AZBIO Corporation, Kita-ku, Osaka, JP;
Abstract
(Problems) To provide a therapeutic agent for infections comprising granulysin as an active ingredient which has little side effect and no cytotoxicity and to which bacteria can hardly acquire resistance, and a treatment method using the same. (Means for Solving Problems) The present invention provides a therapeutic agent for infections comprising as active ingredient: 15K granulysin, a combination of 15K granulysin and 15K granulysin in vivo expression vector, a combination of 15K granulysin and at least one interleukin selected from IL-6, IL-23 or IL-27, a combination of 15K granulysin in vivo expression vector and at least one interleukin selected from IL-6, IL-23 or IL-27, or a combination of 15K granulysin in vivo expression vector and HSP65DNA and IL-12DNA in vivo expression vector, which enhances killing effects on bacteria and has less side effect, and to which bacteria can hardly acquire resistance, and a treatment method using the same.